I wouldn't have said Federer was not taking it seriously. I think the Del Potro match took it out of him (I know Murray has played all that mixed doubles, but come on, playing mixed doubles isn't like going 19-17 in a final set against Del Potro who definitely was taking the Olympics seriously as can be seen by how pumped he was about getting bronze.
But overall Murray played the best match he has done in a big game, and he blew Federer away.
I don't think this should really surprise people though. I would have said if Federer played Murray 10 times in a major final I would expect Federer to win 7 or 8 and Murray to win 2 or 3. The probabilities of it mean that at some point Federer would be slightly off his game when Murray is on hot form and Murray would win that one. I don't see that as being a change in the balance of power, although Federer's age may mean in about 2 years there is a change in the balance between him and Murray.
Will this be the biggest success of Murray's career? Possibly. Depends on how Nadal's fitness recovers. As Federer ages, if Nadal never comes back to being the same player, then we'll have about 3-4 years of Djokovic and Murray at the top, and I think Murray might sneak a Grand Slam or two off Djokovic. If Nadal comes back to being the force of old then it will be Nadal who takes those Slams off Djokovic.